The second European School in Luxembourg was formally opened in 2004. New buildings are currently under construction on the border of the neighbouring communes of Bertrange and Mamer. Opening of the new site is scheduled for school year 2012/2013. Until the opening of the new buildings, the Luxembourg II school consists only of nursery and primary cycles. The secondary cycle is activated at the Luxembourg I school. The nursery classes are hosted in the same building of the nursery classes of the Luxembourg I school in Luxembourg-Kirchberg, while the primary cycle is located in temporary prefabricated buildings (so called "Village Pédagogique"), also in Luxembourg-Kirchberg.
The current Director of the European School Luxembourg II is Emmanuel de Tournemire (France), who replaced Paul Schiltz (Luxembourg), Director during the period 2004-2010.